{"title":"DBCO PEG","description":"\u003cp data-mce-fragment=\"1\"\u003eThe strain-promoted alkyne-azide cycloaddition (SPAAC) has gained widespread adoption as a bioorthogonal reaction, finding extensive applications across diverse fields due to its distinguished attributes of high efficiency, rapidity, selectivity, and bioorthogonality. Notably, SPAAC reactions do not require additional stimuli such as light, heat, ultrasound, or catalysts. The impetus for this reaction originates from the intrinsic strain present in the active cyclic alkynes. Over time, various cyclooctyne derivatives have been developed and meticulously examined for their reactivity in SPAAC reactions with azides.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eDBCO PEG represents a specific category of PEG linker featuring a highly reactive DBCO (Dibenzocyclooctyne) group. DBCO exhibits the capability to react with azide groups without a catalyst through a strain-promoted click reaction. This reaction can be conducted either in an organic solvent or under mild buffer conditions and holds the advantage of not affecting other functional groups present in biological samples. DBCO is instrumental for bioconjugation in live cells, non-living samples, and whole organisms.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eExemplary DBCO PEG products include:\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e1. DBCO-PEG4-DBCO: A PEG linker characterized by two DBCO groups and a hydrophilic PEG spacer arm.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e2. DBCO-PEG4-amido Mal: A bioorthogonal linker featuring azide and sulfhydryl reactivity, with distinct functional groups at each end.\u003c\/p\u003e","products":[{"product_id":"bis-dbco-peg2","title":"Bis-DBCO-PEG2","description":"","brand":"Precise PEG LLC.","offers":[{"title":"100 mg","offer_id":47136524239137,"sku":"AG-2191Q4","price":513.0,"currency_code":"USD","in_stock":true},{"title":"250 mg","offer_id":47136524304673,"sku":"AG-2191Q5","price":775.0,"currency_code":"USD","in_stock":true},{"title":"500 mg","offer_id":47136524337441,"sku":"AG-2191Q6","price":1170.0,"currency_code":"USD","in_stock":true},{"title":"1 g","offer_id":47136524206369,"sku":"AG-2191Q1","price":1872.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0824\/3934\/0321\/products\/Bis-DBCO-PEG2-AG-2191.png?v=1707251277"},{"product_id":"bis-dbco-peg3","title":"Bis-DBCO-PEG3","description":"","brand":"Precise PEG LLC.","offers":[{"title":"100 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