Collection: Acrylate PEG

Acrylate PEG refers to a variant of polyethylene glycol characterized by homobifunctional or heterbifunctional acrylate end groups, affording it the capability to modify proteins, peptides, and various materials.

The inclusion of the acrylate group facilitates radical or UV-initiated polymerization, along with thiol-ene reactions via Michael Addition. The acrylate functional group further enables the construction of polymers from the oligomeric polyethylene glycol monomer. Moreover, the acrylate functional end group of acrylate-substituted PEG can undergo reactions with thiol functional groups, such as those found in Cysteine residues, resulting in the formation of thioethers. By initially polymerizing these PEG compounds and subsequently combining the polymerized PEG compounds with proteins possessing thiol moieties, an effective immobilization of proteins onto surfaces can be achieved. Alternatively, proteins can be enclosed within a polymeric matrix, thereby offering additional versatility in applications.