Isoindolinone Glutarimides | PROTAC Ligands for Cereblon – Precise PEG LLC

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198 Results

3-(5-(azetidin-3-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione TFA salt

3-(5-(azetidin-3-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione TFA salt

3-(4-(6-aminohex-1-yn-1-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione

New

3-(4-(6-aminohex-1-yn-1-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione

4-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)amino)butanoic acid

New

4-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)amino)butanoic acid

3-(5-(7-((1-(4-aminophenyl)piperidin-4-yl)methyl)-2,7-diazaspiro[3.5]nonan-2-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione

New

3-(5-(7-((1-(4-aminophenyl)piperidin-4-yl)methyl)-2,7-diazaspiro[3.5]nonan-2-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione

3-(5-(7-(azetidin-3-ylmethyl)-2,7-diazaspiro[3.5]nonan-2-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione

New

3-(5-(7-(azetidin-3-ylmethyl)-2,7-diazaspiro[3.5]nonan-2-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione

3-(6-(7-(azetidin-3-ylmethyl)-2,7-diazaspiro[3.5]nonan-2-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione

New

3-(6-(7-(azetidin-3-ylmethyl)-2,7-diazaspiro[3.5]nonan-2-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione

3-(6-fluoro-1-oxo-5-(2-(piperidin-4-ylmethyl)-2,7-diazaspiro[3.5]nonan-7-yl)isoindolin-2-yl)piperidine-2,6-dione

New

3-(6-fluoro-1-oxo-5-(2-(piperidin-4-ylmethyl)-2,7-diazaspiro[3.5]nonan-7-yl)isoindolin-2-yl)piperidine-2,6-dione

3-(1-oxo-4-(7-(piperidin-4-ylmethyl)-2,7-diazaspiro[3.5]nonan-2-yl)isoindolin-2-yl)piperidine-2,6-dione

New

3-(1-oxo-4-(7-(piperidin-4-ylmethyl)-2,7-diazaspiro[3.5]nonan-2-yl)isoindolin-2-yl)piperidine-2,6-dione

3-(1-oxo-6-(7-(piperidin-4-ylmethyl)-2,7-diazaspiro[3.5]nonan-2-yl)isoindolin-2-yl)piperidine-2,6-dione

New

3-(1-oxo-6-(7-(piperidin-4-ylmethyl)-2,7-diazaspiro[3.5]nonan-2-yl)isoindolin-2-yl)piperidine-2,6-dione

3-(1-oxo-5-(7-(piperidin-4-ylmethyl)-2,7-diazaspiro[3.5]nonan-2-yl)isoindolin-2-yl)piperidine-2,6-dione

New

3-(1-oxo-5-(7-(piperidin-4-ylmethyl)-2,7-diazaspiro[3.5]nonan-2-yl)isoindolin-2-yl)piperidine-2,6-dione

(R)-3-(1-oxo-6-(7-(piperidin-4-ylmethyl)-2,7-diazaspiro[3.5]nonan-2-yl)isoindolin-2-yl)piperidine-2,6-dione

New

(R)-3-(1-oxo-6-(7-(piperidin-4-ylmethyl)-2,7-diazaspiro[3.5]nonan-2-yl)isoindolin-2-yl)piperidine-2,6-dione

3-(1-oxo-6-(2,7-diazaspiro[3.5]nonan-2-yl)isoindolin-2-yl)piperidine-2,6-dione

3-(1-oxo-6-(2,7-diazaspiro[3.5]nonan-2-yl)isoindolin-2-yl)piperidine-2,6-dione

tert-butyl 2-(2-(2,6-dioxopiperidin-3-yl)-3-oxoisoindolin-5-yl)-2,7-diazaspiro[3.5]nonane-7-carboxylate

tert-butyl 2-(2-(2,6-dioxopiperidin-3-yl)-3-oxoisoindolin-5-yl)-2,7-diazaspiro[3.5]nonane-7-carboxylate

3-(1-oxo-5-(4-((1-(2-(piperazin-1-yl)acetyl)piperidin-4-yl)methyl)piperazin-1-yl)isoindolin-2-yl)piperidine-2,6-dione

3-(1-oxo-5-(4-((1-(2-(piperazin-1-yl)acetyl)piperidin-4-yl)methyl)piperazin-1-yl)isoindolin-2-yl)piperidine-2,6-dione

3-(1-oxo-5-(4-((1-(2-oxo-2-(piperazin-1-yl)ethyl)piperidin-4-yl)methyl)piperazin-1-yl)isoindolin-2-yl)piperidine-2,6-dione

3-(1-oxo-5-(4-((1-(2-oxo-2-(piperazin-1-yl)ethyl)piperidin-4-yl)methyl)piperazin-1-yl)isoindolin-2-yl)piperidine-2,6-dione

(S)-4-((4-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)piperazin-1-yl)methyl)benzoic acid

(S)-4-((4-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)piperazin-1-yl)methyl)benzoic acid

4-((4-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)piperazin-1-yl)methyl)benzoic acid

4-((4-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)piperazin-1-yl)methyl)benzoic acid

4-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)ethynyl)-2-(2,2,2-trifluoroacetamido)benzoic acid

4-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)ethynyl)-2-(2,2,2-trifluoroacetamido)benzoic acid

4-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)ethynyl)benzoic acid

4-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)ethynyl)benzoic acid

2-(4-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)ethynyl)-[1,4'-bipiperidin]-1'-yl)acetic acid

2-(4-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)ethynyl)-[1,4'-bipiperidin]-1'-yl)acetic acid

3-(1-oxo-5-(piperidin-4-ylamino)isoindolin-2-yl)piperidine-2,6-dione

3-(1-oxo-5-(piperidin-4-ylamino)isoindolin-2-yl)piperidine-2,6-dione

3-(1-oxo-5-(piperidin-4-yloxy)isoindolin-2-yl)piperidine-2,6-dione

3-(1-oxo-5-(piperidin-4-yloxy)isoindolin-2-yl)piperidine-2,6-dione

3-(5-(methyl(piperidin-4-yl)amino)-1-oxoisoindolin-2-yl)piperidine-2,6-dione

3-(5-(methyl(piperidin-4-yl)amino)-1-oxoisoindolin-2-yl)piperidine-2,6-dione

3-(5-(((methyl-d3)(piperidin-4-yl)amino)methyl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione

3-(5-(((methyl-d3)(piperidin-4-yl)amino)methyl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione

3-(5-((methyl(piperidin-4-yl)amino)methyl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione

3-(5-((methyl(piperidin-4-yl)amino)methyl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione

(S)-3-(5-((R)-3-(dimethoxymethyl)pyrrolidin-1-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione

(S)-3-(5-((R)-3-(dimethoxymethyl)pyrrolidin-1-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione

3-(4-fluoro-1-oxo-5-(4-((1-(piperidin-4-ylmethyl)piperidin-4-yl)methyl)piperazin-1-yl)isoindolin-2-yl)piperidine-2,6-dione

3-(4-fluoro-1-oxo-5-(4-((1-(piperidin-4-ylmethyl)piperidin-4-yl)methyl)piperazin-1-yl)isoindolin-2-yl)piperidine-2,6-dione

(S)-3-(6-oxo-6,8-dihydro-2H,7H-spiro[furo[2,3-e]isoindole-3,4'-piperidin]-7-yl-2,2-d2)piperidine-2,6-dione

(S)-3-(6-oxo-6,8-dihydro-2H,7H-spiro[furo[2,3-e]isoindole-3,4'-piperidin]-7-yl-2,2-d2)piperidine-2,6-dione

3-(4-methoxy-1-oxo-5-(piperazin-1-yl)isoindolin-2-yl)piperidine-2,6-dione

3-(4-methoxy-1-oxo-5-(piperazin-1-yl)isoindolin-2-yl)piperidine-2,6-dione

3-(6-methoxy-1-oxo-5-(piperazin-1-yl)isoindolin-2-yl)piperidine-2,6-dione

3-(6-methoxy-1-oxo-5-(piperazin-1-yl)isoindolin-2-yl)piperidine-2,6-dione

3-(1-oxo-4-(((R)-pyrrolidin-3-yl)amino)isoindolin-2-yl)piperidine-2,6-dione

3-(1-oxo-4-(((R)-pyrrolidin-3-yl)amino)isoindolin-2-yl)piperidine-2,6-dione

1-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)piperidine-4-carboxylic acid

1-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)piperidine-4-carboxylic acid

2-((R)-2-((S)-2,6-dioxopiperidin-3-yl)-1-oxo-2,3,5a,6,8,9-hexahydro-1H-pyrazino[1',2':4,5][1,4]oxazino[2,3-e]isoindol-7(5H)-yl)acetic acid

2-((R)-2-((S)-2,6-dioxopiperidin-3-yl)-1-oxo-2,3,5a,6,8,9-hexahydro-1H-pyrazino[1',2':4,5][1,4]oxazino[2,3-e]isoindol-7(5H)-yl)acetic acid

(R)-3-((S)-1-oxo-1,3,5,5a,6,7,8,9-octahydro-2H-pyrazino[1',2':4,5][1,4]oxazino[2,3-e]isoindol-2-yl)piperidine-2,6-dione

(R)-3-((S)-1-oxo-1,3,5,5a,6,7,8,9-octahydro-2H-pyrazino[1',2':4,5][1,4]oxazino[2,3-e]isoindol-2-yl)piperidine-2,6-dione

(S)-3-((R)-1-oxo-1,3,5,5a,6,7,8,9-octahydro-2H-pyrazino[1',2':4,5][1,4]oxazino[2,3-e]isoindol-2-yl)piperidine-2,6-dione

(S)-3-((R)-1-oxo-1,3,5,5a,6,7,8,9-octahydro-2H-pyrazino[1',2':4,5][1,4]oxazino[2,3-e]isoindol-2-yl)piperidine-2,6-dione

5-(4-(dimethoxymethyl)piperidin-1-yl)-2-(2,6-dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione

5-(4-(dimethoxymethyl)piperidin-1-yl)-2-(2,6-dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione

2-(2,6-dioxopiperidin-3-yl)-5-(4-((1-(piperidin-4-ylmethyl)piperidin-4-yl)methyl)piperazin-1-yl)isoindoline-1,3-dione

2-(2,6-dioxopiperidin-3-yl)-5-(4-((1-(piperidin-4-ylmethyl)piperidin-4-yl)methyl)piperazin-1-yl)isoindoline-1,3-dione

(S)-3-(6-oxo-6,8-dihydro-2H,7H-spiro[furo[2,3-e]isoindole-3,4'-piperidin]-7-yl)piperidine-2,6-dione

(S)-3-(6-oxo-6,8-dihydro-2H,7H-spiro[furo[2,3-e]isoindole-3,4'-piperidin]-7-yl)piperidine-2,6-dione

4-(4-(aminomethyl)piperidin-1-yl)-N-(2,6-dioxopiperidin-3-yl)-2-methoxybenzamide

4-(4-(aminomethyl)piperidin-1-yl)-N-(2,6-dioxopiperidin-3-yl)-2-methoxybenzamide

2-(2,6-dioxopiperidin-3-yl)-4-methoxy-6-(piperazin-1-yl)isoindoline-1,3-dione

2-(2,6-dioxopiperidin-3-yl)-4-methoxy-6-(piperazin-1-yl)isoindoline-1,3-dione

3-(1-oxo-4-(((S)-pyrrolidin-3-yl)amino)isoindolin-2-yl)piperidine-2,6-dione

3-(1-oxo-4-(((S)-pyrrolidin-3-yl)amino)isoindolin-2-yl)piperidine-2,6-dione

2-(2,6-dioxopiperidin-3-yl)-4-(((R)-pyrrolidin-3-yl)amino)isoindoline-1,3-dione

2-(2,6-dioxopiperidin-3-yl)-4-(((R)-pyrrolidin-3-yl)amino)isoindoline-1,3-dione

1-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)piperidine-4-carboxylic acid

1-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)piperidine-4-carboxylic acid

(R)-3-(1-oxo-5-(4-(piperidin-4-ylmethyl)piperazin-1-yl)isoindolin-2-yl)piperidine-2,6-dione

(R)-3-(1-oxo-5-(4-(piperidin-4-ylmethyl)piperazin-1-yl)isoindolin-2-yl)piperidine-2,6-dione

(S)-3-(1-oxo-5-(4-(piperidin-4-ylmethyl)piperazin-1-yl)isoindolin-2-yl)piperidine-2,6-dione

(S)-3-(1-oxo-5-(4-(piperidin-4-ylmethyl)piperazin-1-yl)isoindolin-2-yl)piperidine-2,6-dione

3-(1-oxo-5-(4-(piperidin-4-ylmethyl)piperazin-1-yl)isoindolin-2-yl)piperidine-2,6-dione

3-(1-oxo-5-(4-(piperidin-4-ylmethyl)piperazin-1-yl)isoindolin-2-yl)piperidine-2,6-dione

1-((1-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)azetidin-3-yl)methyl)piperidine-4-carboxylic acid

1-((1-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)azetidin-3-yl)methyl)piperidine-4-carboxylic acid

1-(1-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)azetidin-3-yl)piperidine-4-carboxylic acid

1-(1-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)azetidin-3-yl)piperidine-4-carboxylic acid

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