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PEG Linkers

Polyethylene glycol (PEG) linkers and PEGylation reagents are widely used tools in bioconjugation and drug development to improve the performance of biomolecules and small-molecule therapeutics. PEG linkers consist of flexible, hydrophilic chains of polyethylene glycol that can be functionalized with reactive groups (e.g., NHS esters, maleimides, azides) to enable efficient coupling to proteins, peptides, antibodies, or other payloads. Through PEGylation these reagents help enhance aqueous solubility, reduce aggregation, and minimize non-specific interactions, while also increasing molecular stability and extending systemic circulation half-life by reducing renal clearance and proteolytic degradation. As a result, PEG linkers play a critical role in applications such as antibody–drug conjugates (ADCs), targeted protein degraders (TPDs), nanoparticle and lipid delivery systems, and diagnostic probes, where controlled spacing, flexibility, and biocompatibility are essential for optimal biological performance.

3019 Results

3019 Results

Azido-PEG3-Thiol

from $456

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per

from $456

Unit price
per

DOTA-GA(tBu)4-PFP

from $350

Unit price
per

from $350

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per

DOTA-PEG4-TFP Ester xTFA Salt

from $500

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per

from $500

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NH-bis(m-PEG4)

from $625

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per

from $625

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per

Amino-PEG7-Alcohol

from $1,080

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per

from $1,080

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per

NH-bis(PEG8-Acid)

from $300

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per

from $300

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Azido-PEG4-Thiol

from $499

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per

from $499

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per

m-PEG3-Aldehyde

from $215

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per

from $215

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endo BCN-PEG3-NHS Ester

from $480

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per

from $480

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DBCO-PEG24-NHS Ester

from $380

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from $380

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Amino-PEG3-Alcohol

from $350

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from $350

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Aminooxy-PEG8-Azide

from $480

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from $480

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Bromo-PEG8-CH2COOH

from $820

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from $820

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N-(NHS ester-PEG3)-N-bis(PEG3-Mal)

from $640

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from $640

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DOTA-GA(tBu)4-PEG4-Acid

from $420

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per

from $420

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Azido-PEG45-Alcohol

from $270

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from $270

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m-PEG4-Thiol

from $333

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per

from $333

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per

endo BCN-PEG4-Alcohol

from $520

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per

from $520

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per

DOTA-PEG4-Amine xTFA Salt

from $650

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per

from $650

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DOTA-PEG23-Amido Mal xTFA Salt

from $650

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per

from $650

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m-PEG10-Alcohol

from $570

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per

from $570

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per

m-PEG3-Acrylate

from $350

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per

from $350

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Mal-PEG1-NHS Ester

from $405

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per

from $405

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Fmoc-N-Amido-PEG8-CH2COOH

from $680

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per

from $680

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per

Azido-PEG16-NHS Ester

from $201

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per

from $201

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per

Azido-PEG8-Hydrazide

from $646

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per

from $646

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Azido-PEG2-Acid

from $228

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per

from $228

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Biotin-PEG20-Acid

from $392

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per

from $392

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Acid-PEG17-t-Bu Ester

from $385

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per

from $385

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Azido-PEG5-Thiol

from $565

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per

from $565

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Azido-PEG2-Thiol

from $565

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per

from $565

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Amino-PEG3-Thiol

from $271

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per

from $271

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per

Amino-PEG5-Alcohol

from $960

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per

from $960

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Amino-PEG10-Bn Ester

from $840

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per

from $840

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per

Amido Mal-PEG4-Amine TFA salt

from $460

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per

from $460

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per

OH-PEGE4-NHS Ester

from $750

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per

from $750

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Cbz-N-amido-PEG3-amine

from $335

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from $335

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Cbz-N-amido-PEG8-amine

from $840

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from $840

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Amino-PEG27-Acid

from $1,080

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per

from $1,080

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per

Amino-PEG22-Acid

from $900

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per

from $900

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Amino-PEG26-Acid

from $1,020

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from $1,020

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Amino-PEG21-Acid

from $850

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from $850

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endo BCN-PEG23-Amine

from $1,200

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from $1,200

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from $720

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Bromo-PEG15-Boc-Amine

from $600

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from $600

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t-Boc-N-methyl-Amido-PEG1-Bromide

from $730

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per

from $730

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t-Boc-N-methyl-Amido-PEG4-Alcohol

from $300

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per

from $300

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t-Boc-N-methyl-Amido-PEG2-Alcohol

from $310

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per

from $310

Unit price
per