Biotin PEG reagents represent a category of PEG linkers featuring a biotin moiety tethered to a PEG spacer, specifically designed for biotinylation purposes. The high affinity of biotin for avidin and streptavidin, coupled with the water-solubilizing effect of the PEG spacer, enhances the solubility of biotinylated molecules and mitigates protein aggregation in solution. The elongated and flexible nature of the PEG spacer also serves to minimize steric hindrance during avidin binding. Biotin PEG reagents find versatile applications in detection, immobilization, targeting, protein labeling, and nonradioactive purification. PrecisePEG stands as a reliable source for high-quality biotin PEG reagents, ensuring consistent and dependable outcomes in research endeavors.
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