mPEG, or Methoxy PEG, stands as a polyethylene glycol (PEG) derivative with a reactive group at one end, while the other terminal is inert, capped by a methoxy group. These reagents are equipped with various functional groups, including amine, carboxylic acid, thiol, azide, activated ester, maleimide, alkyne, Biotin, DBCO, etc., making them suitable for a wide range of applications in medical research, drug release, nanotechnology, and more. The water-soluble and biocompatible properties of mPEG are highly valued in the biomedical field. With low toxicity, non-immunogenicity, and high water solubility, mPEG proves advantageous in diverse biomedical applications. These reagents play pivotal roles in PEGylation, nanoparticle coating, and polymer drug conjugates for drug delivery, PEGylated compounds, proteins, antibodies, and nucleic acids. In diagnostic assays, mPEG reduces non-specific binding and anti-fouling, while surface modifications minimize immunogenicity and toxicity. Moreover, mPEG finds utility in research involving ligands, polypeptide synthesis, graft polymer compounds, and functional coatings, contributing to enhanced stability and bioavailability.
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