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DOTA PEG

DOTA PEG represents a distinct category of PEG linker featuring a DOTA (1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid) unit coupled with a linear polyethylene glycol (PEG) chain. The macrocycle DOTA is recognized as an exceptional and versatile metal chelator, particularly prevalent in PET and SPECT imaging as well as radiotherapy applications. The incorporation of a PEG chain within the linker contributes to the stability and solubility of the conjugate.

Applications of DOTA-PEG linkers encompass:

1. Development of targeted molecular imaging and therapy: Attaching the DOTA PEG linker to a targeting molecule, such as an antibody or a small molecule ligand, enables the selective delivery of therapeutic agents to specific cells or tissues in the body.

2. Advancements in novel therapeutics for cancer, neurological disorders, and inflammatory diseases: DOTA-PEG linkers play a pivotal role in enhancing the pharmacokinetic properties of drug conjugates, including increased half-life and reduced immunogenicity. These attributes contribute to the development of more effective and well-tolerated therapeutic interventions.

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View all... Acrylate PEG Alcohol PEG Amino PEG Aminooxy PEG Aryl PEG Azido PEG BCN PEG Biotin PEG Bromo PEG Bromoacetamide PEG DBCO PEG DNP PEG DOTA PEG DOTAGA PEG m-PEG Maleimide PEG PEG Acid PEG Aldehyde PEG CH2COOH Acid PEG Fluorescent Dye PEG Hydrazide PEG Mesylate PEG NHS Ester PEG PFP Ester PEG Phosphonate PEG Phosphonic Acid PEG SDP Ester PEG Silane PEG Sulfonic Acid PEG TFP Ester PEG Tosylate Propargyl PEG SPDP PEG TCO PEG Tetrazine PEG Thiol PEG Mono-dispersed PEG2000 (PEG45) Branched PEG

PEG Derivatives by Application (Reactivity)

Amine reactive PEG derivatives Bifunctional x-Arm PEG Biotinylation PEG derivatives Carbonyl reactive PEGs Carboxyl reactive PEGs Click chemistry PEGs DOTA chelator PEGs Drug delivery PEGs Dye labeling PEGs Nanoparticle PEGylation Peptide and Protein PEGylation Polymerizable PEGs Specialty PEGylation reagents Surface Reactive PEG Derivatives Thiol reactive PEG derivatives Thiol-ene Crosslinker Chemistry
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DOTA-PEG11-Amido Mal xTFA Salt

DOTA-PEG11-Amido Mal xTFA Salt

from $784.00

from $784.00

In stock

DOTA-PEG11-Amine xTFA Salt

DOTA-PEG11-Amine xTFA Salt

from $980.00

from $980.00

In stock

DOTA-PEG11-Azide xTFA Salt

DOTA-PEG11-Azide xTFA Salt

from $980.00

from $980.00

In stock

DOTA-PEG11-Bromoacetamide xTFA Salt

DOTA-PEG11-Bromoacetamide xTFA Salt

from $655.00

from $655.00

In stock

DOTA-PEG12-TFP Ester xTFA Salt
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DOTA-PEG12-TFP Ester xTFA Salt

$520.00 from $390.00 Save 25%

$520.00 from $390.00 Save 25%

In stock

DOTA-PEG23-Amido Mal xTFA Salt

DOTA-PEG23-Amido Mal xTFA Salt

from $650.00

from $650.00

In stock

DOTA-PEG23-Amine xTFA Salt

DOTA-PEG23-Amine xTFA Salt

from $446.00

from $446.00

In stock

DOTA-PEG23-Azide xTFA Salt
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DOTA-PEG23-Azide xTFA Salt

$1,250.00 from $937.50 Save 25%

$1,250.00 from $937.50 Save 25%

In stock

DOTA-PEG23-Bromoacetamide xTFA Salt

DOTA-PEG23-Bromoacetamide xTFA Salt

from $740.00

from $740.00

In stock

DOTA-PEG24-TFP Ester xTFA Salt

DOTA-PEG24-TFP Ester xTFA Salt

from $649.00

from $649.00

In stock

DOTA-PEG4-Amido Mal xTFA Salt

DOTA-PEG4-Amido Mal xTFA Salt

from $750.00

from $750.00

In stock

DOTA-PEG4-Amine xTFA Salt
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DOTA-PEG4-Amine xTFA Salt

$650.00 from $487.50 Save 25%

$650.00 from $487.50 Save 25%

In stock

DOTA-PEG4-Azide xTFA Salt

DOTA-PEG4-Azide xTFA Salt

from $650.00

from $650.00

In stock

DOTA-PEG4-Bromoacetamide xTFA Salt

DOTA-PEG4-Bromoacetamide xTFA Salt

from $695.00

from $695.00

In stock

DOTA-PEG4-TFP Ester xTFA Salt

DOTA-PEG4-TFP Ester xTFA Salt

from $500.00

from $500.00

In stock

DOTA-PEG5-Amido Mal xTFA Salt

DOTA-PEG5-Amido Mal xTFA Salt

from $790.00

from $790.00

In stock

DOTA-PEG5-Amine xTFA Salt

DOTA-PEG5-Amine xTFA Salt

from $790.00

from $790.00

In stock

DOTA-PEG5-Azide xTFA Salt
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DOTA-PEG5-Azide xTFA Salt

$680.00 from $510.00 Save up to 25%

$680.00 from $510.00 Save up to 25%

In stock

DOTA-PEG5-Bromoacetamide xTFA Salt

DOTA-PEG5-Bromoacetamide xTFA Salt

from $750.00

from $750.00

In stock

DOTA-PEG6-TFP Ester xTFA Salt

DOTA-PEG6-TFP Ester xTFA Salt

from $680.00

from $680.00

In stock

DOTA-PEG7-Amido Mal xTFA Salt
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DOTA-PEG7-Amido Mal xTFA Salt

$728.00 from $546.00 Save 25%

$728.00 from $546.00 Save 25%

In stock

DOTA-PEG7-Amine xTFA Salt

DOTA-PEG7-Amine xTFA Salt

from $900.00

from $900.00

In stock

DOTA-PEG7-Azide xTFA Salt
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DOTA-PEG7-Azide xTFA Salt

$820.00 from $615.00 Save up to 25%

$820.00 from $615.00 Save up to 25%

In stock

DOTA-PEG7-Bromoacetamide xTFA Salt

DOTA-PEG7-Bromoacetamide xTFA Salt

from $720.00

from $720.00

In stock

DOTA-PEG8-TFP Ester xTFA Salt

DOTA-PEG8-TFP Ester xTFA Salt

from $690.00

from $690.00

In stock

DOTA-tris(t-Bu)-Amido-PEG11-Amido Mal

DOTA-tris(t-Bu)-Amido-PEG11-Amido Mal

from $728.00

from $728.00

In stock

DOTA-tris(t-Bu)-Amido-PEG11-Amine
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DOTA-tris(t-Bu)-Amido-PEG11-Amine

$980.00 from $735.00 Save 25%

$980.00 from $735.00 Save 25%

In stock

DOTA-tris(t-Bu)-Amido-PEG11-Azide
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DOTA-tris(t-Bu)-Amido-PEG11-Azide

$3,967.00 from $980.00 Save 25%

$3,967.00 from $980.00 Save 25%

In stock

DOTA-tris(t-Bu)-Amido-PEG11-Bromoacetamide

DOTA-tris(t-Bu)-Amido-PEG11-Bromoacetamide

from $750.00

from $750.00

In stock

DOTA-tris(t-Bu)-Amido-PEG12-NHS Ester

DOTA-tris(t-Bu)-Amido-PEG12-NHS Ester

from $580.00

from $580.00

In stock

DOTA-tris(t-Bu)-Amido-PEG12-TFP Ester

DOTA-tris(t-Bu)-Amido-PEG12-TFP Ester

from $600.00

from $600.00

In stock

DOTA-tris(t-Bu)-Amido-PEG23-Amido Mal

DOTA-tris(t-Bu)-Amido-PEG23-Amido Mal

from $620.00

from $620.00

In stock

DOTA-tris(t-Bu)-Amido-PEG23-Amine

DOTA-tris(t-Bu)-Amido-PEG23-Amine

from $1,250.00

from $1,250.00

In stock

DOTA-tris(t-Bu)-Amido-PEG23-Azide
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DOTA-tris(t-Bu)-Amido-PEG23-Azide

$1,250.00 from $937.50 Save up to 25%

$1,250.00 from $937.50 Save up to 25%

In stock

DOTA-tris(t-Bu)-Amido-PEG23-Bromoacetamide

DOTA-tris(t-Bu)-Amido-PEG23-Bromoacetamide

from $730.00

from $730.00

In stock

DOTA-tris(t-Bu)-Amido-PEG24-NHS Ester

DOTA-tris(t-Bu)-Amido-PEG24-NHS Ester

from $750.00

from $750.00

In stock

DOTA-tris(t-Bu)-Amido-PEG24-TFP Ester

DOTA-tris(t-Bu)-Amido-PEG24-TFP Ester

from $649.00

from $649.00

In stock

DOTA-tris(t-Bu)-Amido-PEG4-Amido Mal
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DOTA-tris(t-Bu)-Amido-PEG4-Amido Mal

$650.00 from $487.50 Save 25%

$650.00 from $487.50 Save 25%

In stock

DOTA-tris(t-Bu)-Amido-PEG4-Amine
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DOTA-tris(t-Bu)-Amido-PEG4-Amine

$650.00 from $487.50 Save 25%

$650.00 from $487.50 Save 25%

In stock

DOTA-tris(t-Bu)-Amido-PEG4-Azide

DOTA-tris(t-Bu)-Amido-PEG4-Azide

from $650.00

from $650.00

In stock

DOTA-tris(t-Bu)-Amido-PEG4-Bromoacetamide
Sale

DOTA-tris(t-Bu)-Amido-PEG4-Bromoacetamide

$650.00 from $487.50 Save 25%

$650.00 from $487.50 Save 25%

In stock

DOTA-tris(t-Bu)-Amido-PEG4-NHS Ester

DOTA-tris(t-Bu)-Amido-PEG4-NHS Ester

from $490.00

from $490.00

In stock

DOTA-tris(t-Bu)-Amido-PEG4-TFP Ester

DOTA-tris(t-Bu)-Amido-PEG4-TFP Ester

from $480.00

from $480.00

In stock

DOTA-tris(t-Bu)-Amido-PEG5-Amido Mal
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DOTA-tris(t-Bu)-Amido-PEG5-Amido Mal

$750.00 from $562.50 Save 25%

$750.00 from $562.50 Save 25%

In stock

DOTA-tris(t-Bu)-Amido-PEG5-Amine

DOTA-tris(t-Bu)-Amido-PEG5-Amine

from $680.00

from $680.00

In stock

DOTA-tris(t-Bu)-Amido-PEG5-Azide

DOTA-tris(t-Bu)-Amido-PEG5-Azide

from $680.00

from $680.00

In stock

DOTA-tris(t-Bu)-Amido-PEG5-Bromoacetamide

DOTA-tris(t-Bu)-Amido-PEG5-Bromoacetamide

from $670.00

from $670.00

In stock

DOTA-tris(t-Bu)-Amido-PEG6-NHS Ester
Sale

DOTA-tris(t-Bu)-Amido-PEG6-NHS Ester

$1,929.00 from $670.00 Save 25%

$1,929.00 from $670.00 Save 25%

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