PEG Acid

PEG acids, constituting a subgroup within PEG compounds, are characterized by a carboxylic acid (COOH) group at one end and another functional group—such as azide, amino, maleimide, or alkynes—at the opposite terminus. These versatile linkers exhibit the capability to couple with amine-containing compounds through the utilization of coupling reagents like HATU and EDC. Furthermore, PEG acids have the capacity to form active esters, including NHS ester or PFP ester, widely employed in bioconjugation processes.

PEG acid functionalities extend to the modification of biomolecules or surfaces featuring free amines, encompassing materials such as quantum dots, self-assembled monolayers, and magnetic particles. The applications of PEG acids span across diverse domains, including medical research, drug-release mechanisms, nanotechnology, new materials research, cell culture, as well as the synthesis of ligands and polypeptides. This versatility positions PEG acids as integral components in an array of scientific and technological advancements.

Acid-PEG-Ethyl Ester

Acid-PEG-Methyl Ester

Carboxy-PEG-Sulfonic Acid