Bromo PEG

Bromo PEG stands as a derivative of polyethylene glycol characterized by a bromide group at one end and another functional group at the opposite terminus. This particular PEG derivative is amenable to bioconjugation and PEGylation processes, achieved through reactions with nucleophiles, particularly thiols. The bromide (Br) moiety readily undergoes substitution reactions, wherein it is replaced by nucleophiles. In the context of bioconjugation, Bromo PEG linkers form sulfide bonds with thiol groups present on biomolecules.

Noteworthy examples of Bromo PEG products include:

1. Bromo-PEG4-acid: A heterobifunctional, PEGylated crosslinker featuring a bromide and a carboxyl group at each end.

2. Bromo-PEG3-azide: A PEG-azide variant designed for copper-free click chemistry applications.

Bromo-PEG-Azide

CH2COOH t-Bu Ester-PEG-Bromide

Propargyl-PEG-Bromide

m-PEG-Bromide

t-Bu Ester-PEG-Bromide